Saffron Yellow (Crocus sativus) Extract in Human Clinical Trials: Doses, Durations, Extract Types and Outcomes
Formulator’s summary: Saffron Yellow (Crocus sativus) is a water-soluble stigma extract powder with a 100:1 ratio and crocins named. It provides yellow-orange colour and saffron flavour for beverages, rice dishes, dairy and bakery. Published human trials of saffron stigma extracts commonly use about 20 to 50 mg per day, within a broad range of roughly 15 to 100 mg per day; that is a literature range for other preparations, not a use level for this powder.
Review at a glance
- Ingredient and form: Saffron Yellow (Crocus sativus) standardised extract powder.
- Extract ratio: 100:1, as stated on the live product page.
- Marker: Crocins are named; the assay result is reported on the specification and the lot certificate of analysis.
- Typical daily range in published human trials of saffron stigma extracts: about 15 to 100 mg, commonly 20 to 50 mg.
What this review covers
This article distinguishes published review literature on saffron from product-specific formulation information. The dose range quoted here describes how saffron stigma extracts are commonly dosed in published human trials. It is not a use level, claim or outcome for Saffron Yellow standardised extract powder. For procurement and formulation comparison, the relevant product attributes are botanical identity, extract ratio, named marker, specification and lot documentation.
Clinical review literature on saffron
Two human clinical review publications identified in the literature search concern saffron and mild-to-moderate depression, and clinical evidence in neurological and psychiatric conditions. Across published trials of standardised saffron stigma extracts, daily amounts are commonly reported at about 20 to 50 mg, with a broad range of roughly 15 to 100 mg per day, usually taken as one or two divided doses. Trial durations are commonly several weeks, often in the region of 6 to 12 weeks.
These ranges describe the studied preparations and populations only. A study-specific quantity or finding must match the studied preparation and population, and it is not transferred to this catalogue powder.
What should formulators compare across saffron preparations?
“Saffron extract” alone does not fully identify a research material. A technical comparison checks botanical identity, plant part, preparation, extract description, marker and assay method, administered amount, route, population and endpoint. Where those details differ or are unreported, the research preparation should not be treated as equivalent to the catalogue powder.
The product page names crocins as the marker. A standardised extract specification identifies the assay marker, method and acceptance range, and a certificate of analysis (COA) records the lot result. A crude botanical powder may identify plant material without establishing a consistent quantified marker assay. This is a specification and batch-documentation distinction, not a physiological one.
What product details are available for Saffron Yellow?
| Specification item | Available product information |
|---|---|
| Botanical identity | Saffron Yellow (Crocus sativus). |
| Plant part and form | Stigma extract powder. |
| Extract ratio | 100:1, as stated on the product page. |
| Named marker | Crocins; assay result on the specification and lot COA. |
| Typical daily range in published human trials of saffron stigma extracts | About 15 to 100 mg per day, commonly 20 to 50 mg. A literature range for other preparations, not a use level for this powder. |
How should documents support qualification?
For lot qualification, a buyer can compare botanical identity, plant part, extract ratio, marker name, assay method, acceptance specification and lot result across the product specification and COA. Storage and handling particulars should also be reviewed against the current product documentation.
The product’s colour and aroma are formulation attributes distinct from clinical endpoints. Crocin is identified in the product information as a colour-associated constituent. Confirm solubility and dispersion behaviour against the current product specification and evaluate the ingredient in the intended matrix.
What can clinical reviews establish about this catalogue powder?
General review publications do not establish a product-specific use level, extract equivalence or outcome for Saffron Yellow standardised extract powder. The catalogue item should be assessed against its own current product documentation. Clinical findings, where considered, remain limited to the preparations and populations studied and are not transferred to this product.
Supplying saffron extract and related ingredients in bulk
Bionutricia lists Saffron Yellow (Crocus sativus) standardised extract powder as a 100:1 bulk ingredient with crocins named. For technical qualification, buyers can request the current specification and lot COA, and R&D sample quantities are available for specification testing. The product page describes packaging and storage particulars; buyers should review the current documents for the required packing configuration and handling conditions. Related catalogue guides cover Saffron Extract Powder, Monk Fruit Extract Powder, and extract ratio versus standardisation. Published quality certifications include FSSC 22000, JAKIM Halal, GMP, HACCP, MeSTI and US FDA facility registration.
Frequently asked questions
What daily amounts are used in published saffron extract trials? Published human trials of saffron stigma extracts commonly use about 20 to 50 mg per day, within a broad range of roughly 15 to 100 mg per day. That range describes other studied preparations and does not set a use level for this powder.
Does the product page state a crocin assay percentage? The assay percentage is not stated on the product page; check the current product specification and lot COA for the marker result and method.
Can clinical review findings be assigned to this catalogue powder? No. The reviews concern saffron research and do not establish equivalence or a product-specific outcome for this powder.
Which details should be checked for lot qualification? Compare botanical identity, plant part, ratio, marker, assay method, acceptance specification, lot result, packaging and storage particulars against current product documents.
Request the product specification
Request the certificate of analysis, specification sheet and a sample of Saffron Yellow (Crocus sativus) Standardized Extract Powder.
