Knowledge: Chayote (Sechium Edule)

Chayote (Sechium Edule)


Chayote (Labu Siam/ Siem), also known as mirliton squash or chocho is one kind of squash that belongs to the gourd family (Cucurbitaceae), originated from Mexico and Latin America but it is now cultivated all around the world.

Chayote is famous for its high nutrients and is a great source of antioxidants. It can be eaten raw or cooked. Chayote is slightly sweet and has taste similar to cucumber. Common recipe for chayote including salads and salsas.

chayote nutrition
  • Rich in nutrients
  • Good source of Vitamin C and Vitamin B9 (folate)
  • Source of antioxidants
  • Antihypertensive effect
  • Reduce blood sugar level
  • Support healthy pregnancy

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Antihypertensive properties

Bivariant analysis
Subject Elderly with hypertension (n = 360)
  1. Before intervention
  2. After intervention
Duration 4 days
Dosage Chayote juice (122 grams of chayote, prepared 180 ml of plain water) – taken an hour or 2 hour before meal
Parameters analyzed Blood pressure measurement
Outcomes Visible benefits
Consumption of chayote juice has median decrease in systolic blood 30 mmHg and diastolic 10 mmHg.
Table 1: Distribution of frequency of elderly people with hypertension based on measurement blood pressure before and after drinking chayote juice.

Functions Chayote juice has effects to reduce blood pressure in elderly with hypertension. By consuming chayote juice, it may help in maintaining and controlling blood pressure of the elderly.

Folate – improves healthy pregnancy

Population-based study
Subject Pregnant women with or without supplementation of folic acid
  1. Without folic acid supplementation
  2. With folic acid supplementation
  3. With folic acid supplementation + multivitamin
  4. With multivitamin supplementation
Duration From 6th to 12th weeks gestation week
Dosage 3 mg FA tablet
Parameters analyzed Comparison of prospective medically recorded data of newborns (birth weight, preterm birth)

Visible benefits

  • The rate of preterm births (7.6%) was significantly lower in folic acid group compared with the reference sample (11.8%).
  • Folic acid alone is the third trimester associated with 0.6 week longer gestational age and a more significant reduction in the rate of preterm births (4.8%).
Functions Chayote, which is rich in folic acid may be a natural source of folic acid for pregnant women.

Reduce blood sugar level

In vivo lab experiment
Subject White male mice with DD Webster strain
  1. Negative control group
  2. Positive control group with STZ 60mg/kgBW
  3. Experimental group I with STZ 60mg/kgBW + EEBLS of 100 mg/kgBW
  4. Experimental group II with STZ 60mg/kgBW + EEBLS 200mg/kgBW

*STZ = streptozotocin
*EEBLS = ekstrak etanol buah labu siam

Duration 28 days
Dose Ethanol extract of chayote at 60 – 200mg/kgBW
Parameters analyzed Blood glucose level measurement
Outcomes Visible benefits
Ethanol extract of chayote administered either in 100 mg/kg or 200 mg/kg decrease blood glucose level in mice
Figure 1: Blood glucose level in mice per week for 28 days.
Chayote extract was given starting from day 5. Black arrow indicates dropping of blood glucose level.

Purple: EEBLS 200 mg
Green: EEBLS 100 mg
Red: positive control
Blue: negative control*Diabetes is induced by streptozotocin (STZ). STZ damages pancreas b cells so that KGD increases.
Functions 200 mg/kg of chayote extract decrease blood sugar content

Antioxidant and Anti-inflammatory properties

Exploratory study
Subject 12 older adults, with an average age of 71 ± 6 years (10 women and 2 men) with a diagnosis of metabolic syndrome (MetS)
  1. Placebo
  2. Chayote extract supplementation
Duration 6 weeks
Dosage 500 mg, 3 times per day
Parameters analyzed Weight different between placebo and GA/HCA-supplemented group

Visible benefits

  • There was a statistically significant decrease in the concentration of lipoperoxidases together with significant increase in total antioxidant status.
  • The oxidative stress index (OxS-Score) showed a statistically significant decrease.
  • Significant decrease in the concentration of TNF-α after treatment was also noted.

Table 1: Markers of oxidative stress during pre- and post-treatment.

Table 1: Markers of inflammation during pre- and post-treatment.

Functions The consumption of the dry fruit of chayote has an antioxidant and anti-inflammatory effect in older adults with metabolic syndrome.
Chayote extract

Chayote Standardized Extract Powder (Sechium Edule)

    • Contains potent antioxidants
    • May promote a healthy weight
    • May support digestive health
    • Rich in Vitamin, antioxidant & Mineral
    • May lower blood pressure
    • Help prevent bone loss