Agaricus blazei Murill (accepted name Agaricus subrufescens) is a medicinal-culinary mushroom whose powder carries native 1,3/1,6-beta-glucan — the marker polysaccharide quantified by enzymatic assay. Bionutricia Extract supplies it in bulk to B2B and OEM formulators from a JAKIM Halal, FSSC 22000, US FDA-registered, GMP, HACCP and MeSTI facility in Malaysia, with a Certificate of Analysis on every lot.


Quick facts for formulators
- Botanical / part:Agaricus blazei Murill (A. subrufescens), whole mushroom
- Type: whole-mushroom powder
- Marker compound: 1,3/1,6-beta-glucan (enzymatic / Megazyme-type assay)
- Form / colour: light-brown powder, characteristic
- Moisture: <10% · pH: 5-7 · Dosage: 500-1000 mg
- Particle size: > 85% through 60 mesh
- Pack sizes: 1 kg · 5 kg · 20 kg
- Certifications: JAKIM Halal facility · FSSC 22000 · US FDA registered · GMP · HACCP · MeSTI · COA per lot
- Clean label: vegan, non-GMO, gluten-free (<20 ppm), not irradiated
- Shelf life: 24 months sealed, cool & dry · Origin: Malaysia
What is Agaricus blazei mushroom powder?
Agaricus blazei Murill — botanically Agaricus subrufescens, and known as the almond mushroom or cogumelo do sol — is a mushroom of Brazilian origin now cultivated widely and valued in East-Asian functional-food traditions. Bionutricia's powder is milled from the whole mushroom into a fine, free-flowing powder that retains its native fibre and characteristic beta-glucan polysaccharides, giving formulators a consistent whole-food mushroom base.
Active compound & standardisation
The marker constituents of Agaricus blazei are its 1,3/1,6-beta-glucans — the branched fungal cell-wall polysaccharides for which this species is particularly noted. Beta-glucan is the value marker for mushroom ingredients and is quantified by an enzymatic method (Megazyme mushroom & yeast beta-glucan / AOAC 995.16 lineage) that distinguishes true beta-glucan from other polysaccharides; the figure is reported on the batch Certificate of Analysis.
How Agaricus works in the body (mechanism)
Fungal beta-(1,3)(1,6)-glucans are recognised by innate-immune pattern-recognition receptors — Dectin-1, complement receptor 3 (CR3) and TLR2/6 — on macrophages, dendritic cells and natural-killer cells. This receptor engagement is the mechanistic basis for the long-standing scientific interest in Agaricus blazei beta-glucans as immunomodulators. Mechanism is provided as scientific background on the mushroom; it is not a claim that this ingredient treats, cures or prevents any condition.
Clinical evidence on Agaricus blazei
Human studies of Agaricus blazei have mostly used a standardised mushroom-blend extract in patient populations. The evidence below is attributed to the cited studies and provided as scientific context — not as a performance claim for this single-species powder.
| Study | Design | Result (attributed to the study) |
|---|---|---|
| Therkelsen et al. 2016 | RCT, ulcerative colitis, n=50, AndoSan blend, 21 days | Reduced clinical symptom index and improved quality-of-life / fatigue scores vs placebo |
| AndoSan Crohn's / birch-allergy studies | RCTs, n=50 (Crohn's) and n=60 (birch-pollen allergy) | Changes in inflammatory/immune markers reported in the studied groups |
| AndoSan oncology adjunct | RCT, non-small-cell lung cancer, n=66 | Explored as a supportive adjunct; described in the study only |
Important context: "AndoSan" is a three-mushroom blend extract (Agaricus blazei with Hericium erinaceus and Grifola frondosa), not our single-species Agaricus powder, and all trials are in patient populations. Results describe the studied preparation, not a Bionutricia finished product. Beta-glucan content on the CoA is the objective quality metric.
Typical specification
| Parameter | Value |
|---|---|
| Botanical source / part | Agaricus blazei Murill (A. subrufescens), whole mushroom |
| Type | Whole-mushroom powder |
| Appearance / colour | Powder, light brown |
| Marker compound | 1,3/1,6-beta-glucan (enzymatic assay; figure on CoA) |
| Moisture | < 10% |
| pH | 5-7 |
| Particle size / mesh | > 85% through 60 mesh |
| Dosage | 500-1000 mg |
| Heavy metals (As, Pb, Cd, Hg) | As ≤ 5 ppm, Pb ≤ 10 ppm, Cd ≤ 0.3 ppm, Hg ≤ 0.5 ppm |
| Microbial | TPC ≤ 10⁴ cfu/g, Y&M ≤ 10³ cfu/g, coliform ≤ 10² cfu/g, E. coli / Salmonella / S. aureus absent |
| Certifications | JAKIM Halal facility, FSSC 22000, US FDA registered, GMP, HACCP, MeSTI |
| Shelf life | 24 months sealed, cool & dry |
| Pack sizes | 1 kg, 5 kg, 20 kg |
| Country of origin | Malaysia |
Full specification and a batch Certificate of Analysis are provided on request. Figures are typical values; confirm the current lot CoA for release data and beta-glucan content.
Applications
Bionutricia supplies the bulk ingredient for B2B formulation; brand owners and manufacturers formulate it into their chosen finished format — capsules, tablets and sachets, mushroom-complex blends, functional beverages and savoury systems.
Why source Agaricus blazei powder from Bionutricia?
Bionutricia Extract has manufactured Malaysian botanical and mushroom ingredients since 2006 under a full halal and international food-safety stack (JAKIM Halal facility, FSSC 22000, US FDA registration, GMP, HACCP, MeSTI), issuing a Certificate of Analysis — including beta-glucan content — on every lot. Bulk OEM, custom milling and packing are available. See the live Agaricus blazei mushroom powder product page for ordering.
Frequently asked questions
Standardised on what / is a COA available? Native 1,3/1,6-beta-glucan quantified by enzymatic assay; batch CoA per lot.
What is it also called?Agaricus subrufescens; almond mushroom, cogumelo do sol, himematsutake.
Is it halal? Produced in a JAKIM Halal-certified facility, also FSSC 22000, US FDA-registered, GMP, HACCP and MeSTI; documentation with each shipment.
What formats can I make? Capsules, tablets, sachets, mushroom blends and beverages — we supply the bulk ingredient; you formulate.
Dosage? Typically 500-1000 mg on a quantum satis basis.
MOQ & lead time? Pack sizes 1 kg, 5 kg, 20 kg; pre-order packing ~1-2 weeks. MOQ & pricing on quotation.
Samples? Paid samples for serious B2B enquiries.
Storage & shelf life? Sealed, cool & dry, away from pests; 24 months when properly stored.
